HERC5 Antibody - BSA Free

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Western Blot: HERC5 Antibody - BSA Free [NBP3-46127] - HEK-293 cells were subjected to SDS PAGE followed by western blot with (HERC5 antibody) at dilution of 1:500

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

HERC5 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit HERC5 Antibody - BSA Free (NBP3-46127) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
hect domain and RLD 5. (Uniprot# Q9UII4)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HERC5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500-1:2000
Theoretical MW
128 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 50% Glycerol, pH (7.3)
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HERC5 Antibody - BSA Free

  • CEB1E3 ISG15--protein ligase HERC5
  • CEBP1
  • cyclin-E binding protein 1
  • Cyclin-E-binding protein 1
  • EC 6.3.2
  • EC 6.3.2.-
  • HECT domain and RCC1-like domain-containing protein 5
  • hect domain and RLD 5
  • HECT E3 ubiquitin ligase
  • probable E3 ubiquitin-protein ligase HERC5

Background

The HERC5 gene encodes for a 1,024 amino acid long, 116kDA E3 1SG15-protein ligase HERC5 protein near a cluster of HERC family genes located on chromosome 4. The protein coded for by the HERC5 gene localizes to the cytoplasm and perinuclear region and works as an interferon-induced E3 protein ligase. In doing so, it controlls ISGylation of protein targets. The HERC5 gene has been researched regarding influenza, malaria, teratoma, angelman syndrom, and carcinoma. The HERC5 gene interacts in interferon signaling, cytokine signaling in the immune system, and negative regulation of RIG-I/MDA4 signaling with interactions in NME2, CCNA2, ERCC2, PITX2, and NME1-NME2 genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional HERC5 Products

Array NBP3-46127

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Bioinformatics

Gene Symbol HERC5