Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
The HERC5 gene encodes for a 1,024 amino acid long, 116kDA E3 1SG15-protein ligase HERC5 protein near a cluster of HERC family genes located on chromosome 4. The protein coded for by the HERC5 gene localizes to the cytoplasm and perinuclear region and works as an interferon-induced E3 protein ligase. In doing so, it controlls ISGylation of protein targets. The HERC5 gene has been researched regarding influenza, malaria, teratoma, angelman syndrom, and carcinoma. The HERC5 gene interacts in interferon signaling, cytokine signaling in the immune system, and negative regulation of RIG-I/MDA4 signaling with interactions in NME2, CCNA2, ERCC2, PITX2, and NME1-NME2 genes.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
51191 |
| Alternate Names |
- CEB1E3 ISG15--protein ligase HERC5
- CEBP1
- cyclin-E binding protein 1
- Cyclin-E-binding protein 1
- EC 6.3.2
- EC 6.3.2.-
- HECT domain and RCC1-like domain-containing protein 5
- hect domain and RLD 5
- HECT E3 ubiquitin ligase
- probable E3 ubiquitin-protein ligase HERC5
|
Research Areas for HERC5
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
