HERC5 Products

HERC5 Antibody
HERC5 Antibody
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
HERC5 Antibody
HERC5 Antibody
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HERC5 Antibody
HERC5 Antibody
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Recombinant Human HERC5 His P ...
Recombinant Human HERC5 His Protein
Species: Hu
Applications: PAGE
HERC5 Recombinant Protein Ant ...
HERC5 Recombinant Protein Antigen
Species: Hu
Applications: AC


The HERC5 gene encodes for a 1,024 amino acid long, 116kDA E3 1SG15-protein ligase HERC5 protein near a cluster of HERC family genes located on chromosome 4. The protein coded for by the HERC5 gene localizes to the cytoplasm and perinuclear region and works as an interferon-induced E3 protein ligase. In doing so, it controlls ISGylation of protein targets. The HERC5 gene has been researched regarding influenza, malaria, teratoma, angelman syndrom, and carcinoma. The HERC5 gene interacts in interferon signaling, cytokine signaling in the immune system, and negative regulation of RIG-I/MDA4 signaling with interactions in NME2, CCNA2, ERCC2, PITX2, and NME1-NME2 genes.


Entrez Human
Uniprot Human
Product By Gene ID 51191
Alternate Names
  • CEB1E3 ISG15--protein ligase HERC5
  • CEBP1
  • cyclin-E binding protein 1
  • Cyclin-E-binding protein 1
  • EC 6.3.2
  • EC 6.3.2.-
  • HECT domain and RCC1-like domain-containing protein 5
  • hect domain and RLD 5
  • HECT E3 ubiquitin ligase
  • probable E3 ubiquitin-protein ligase HERC5

Research Areas for HERC5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for HERC5

Learn more about PTMs related to HERC5.


Bioinformatics Tool for HERC5

Discover related pathways, diseases and genes to HERC5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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