Western Blot: Viperin Antibody [NBP2-03971] - Analysis of viperin using viperin polyclonal antibody. Human brain lysate in the absence (1) and presence (2) of immunizing peptide, mouse brain (3) and rat brain (4) lysate ...read more
Immunohistochemistry-Paraffin: Viperin Antibody [NBP2-03971] - Analysis of viperin using viperin polyclonal antibody. Human rectum tissue probed with viperin antibody at 5 ug/ml.
The amino acid sequence used as immunogen is 100% homologous in white-cheeked gibbon, chinese hamster, common chimpanzee, new world monkey, panda, african bush elephant and orangutan, 95% in horse, wild turkey, opossum, platypus, 89% in western clawed frog, rabbit, zebra finch, chicken, 79% in carolina anole, and 63% homologous in zebrafish and sablefish.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.2 ml PBS and 0.05% BSA
0.05% Sodium Azide
Protein A purified
Alternate Names for Viperin Antibody
Cytomegalovirus-induced gene 5 protein
radical S-adenosyl methionine domain containing 2
radical S-adenosyl methionine domain-containing protein 2
Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies. Additionally, viperin antibodies provide useful information for analysis of specific cell types responsive to interferon making it valuable for phenotyping studies complementing mechanism of action analysis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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