Helios Peptide

Product Discontinued

Helios Peptide Summary

• Description: A peptide to IKZF2.
• Immunogen: Portions of this peptide represent the epitopes that are recognized by anti-Helios (NBP1-97741). The peptide blocks the ability of anti-Helios (NBP1-97741) to bind Helios
• Specificity: This peptide is specific to antibody NBP1-97741 only.
• Protein/Peptide Type: Peptide
• Gene: IKZF2

Applications/Dilutions

• Dilutions:
  • Antibody Competition

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-buffered Saline and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml

Alternate Names for Helios Peptide

• Helios
• IKAROS family zinc finger 2 (Helios)
• Ikaros family zinc finger protein 2
• IKZF2
• MGC34330
• subfamily 1A, 2 (Helios)
• zinc finger DNA binding protein Helios
• zinc finger protein Helios
• ZNF1A2
• ZNFN1A2

Background

HELIOS encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IKZF2