Helios Products

Description

HELIOS encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Bioinformatics

Entrez	22807 Human
Uniprot	NP_001072994.1 Human Q9UKS7 Human NP_057344 Human NM_001079526 Human
Product By Gene ID	22807
Alternate Names	MGC34330 zinc finger protein Helios Helios zinc finger DNA binding protein Helios ZNFN1A2 ZNF1A2 HELIOS Ikaros family zinc finger protein 2 subfamily 1A, 2 (Helios) IKAROS family zinc finger 2 (Helios)

Diseases related to Helios

Discover more about diseases related to Helios.

Leukemia
Malignant Neoplasms
Lymphoma
Adult T-cell Lymphoma/leukemia
Acute Lymphocytic Leukemia
Myeloid Leukemia, Chronic
Carcinoma
Myeloid Leukemia
Autoimmune Diseases
Decreased Immunologic Activity [pe]
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Leukemogenesis
Blast Phase
Autoimmunity
Burkitt Lymphoma
Diabetic Nephropathy
Hereditary Hemorrhagic Telangiectasia
Kidney Neoplasm
Neoplasms
Renal Cell Carcinoma

Pathways for Helios

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Pathogenesis
Cell Activation
T Cell Activation
Localization
Lymphocyte Differentiation
Secretion

Research Areas for Helios

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Adaptive Immunity
Immunology

PTMs for Helios

Learn more about PTMs related to Helios.

Phosphorylation
Cleavage

Bioinformatics Tool for Helios

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