Guinea Pig IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• Reactivity: Gp
• Applications: ELISA
• Conjugate: Biotin

Guinea Pig IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Il1b

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Guinea Pig IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• catabolin
• IL1 beta
• IL-1 beta
• IL-1
• IL1B
• IL-1b
• IL1-BETA
• IL-1F2
• IL1F2IL-1 beta
• interleukin 1, beta
• interleukin-1 beta
• preinterleukin 1 beta
• pro-interleukin-1-beta

Background

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Publications for IL-1 beta/IL-1F2 (DY6226)(2)

Publications using DY6226

• M Galasso, JJ Feld, Y Watanabe, M Pipkin, C Summers, A Ali, R Qaqish, M Chen, RVP Ribeiro, K Ramadan, L Pires, VS Bagnato, C Kurachi, V Cherepanov, G Moonen, A Gazzalle, TK Waddell, M Liu, S Keshavjee, BC Wilson, A Humar, M Cypel Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion Nat Commun, 2019-01-29;10(1):481. 2019-01-29 [PMID: 30696822] (Porcine)
• Y Wang, P Zhu, J Tan, Z Liu, W Qu, L Liu, Z Li Therapeutic Effects of Kangzhi Syrup in a Guinea Pig Model of Ovalbumin-Induced Cough Variant Asthma Evid Based Complement Alternat Med, 2018-05-23;2018(0):5867835. 2018-05-23 [PMID: 29951106] (Guinea Pig)

FAQs for IL-1 beta/IL-1F2 (DY6226). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Il1b