GRAIL/RNF128 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: mFluor Violet 500 SE

GRAIL/RNF128 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: E. coli-derived recombinant human GRAIL/RNF128
  Val42-Pro161
  Accession # Q8TEB7
• Specificity: Detects human GRAIL/RNF128 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: RNF128
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GRAIL/RNF128 Antibody [mFluor Violet 500 SE]

• EC 6.3.2
• EC 6.3.2.-
• FLJ23516
• Gene related to anergy in lymphocytes protein
• GRAIL
• ring finger protein 128GRAILE3 ubiquitin-protein ligase RNF128
• RNF128

Background

The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNF128