GRAIL/RNF128 Antibody [PerCP]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PerCP

GRAIL/RNF128 Antibody [PerCP] Summary

• Immunogen: E. coli-derived recombinant human GRAIL/RNF128
  Val42-Pro161
  Accession # Q8TEB7
• Specificity: Detects human GRAIL/RNF128 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: RNF128
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for GRAIL/RNF128 Antibody [PerCP]

• EC 6.3.2
• EC 6.3.2.-
• FLJ23516
• Gene related to anergy in lymphocytes protein
• GRAIL
• ring finger protein 128GRAILE3 ubiquitin-protein ligase RNF128
• RNF128

Background

The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNF128