GPR137B Antibody

Immunocytochemistry/Immunofluorescence: GPR137B Antibody [NLS788] - Analysis of anti-GPR137B / TM7SF1 antibody with HEK293 human embryonic kidney cells.

Immunohistochemistry-Paraffin: GPR137B Antibody [NLS788] - Brain, glioblastoma

Immunocytochemistry/Immunofluorescence: GPR137B Antibody [NLS788] - Analysis of anti-GPR137B / TM7SF1 antibody with untransfected HEK293 human embryonic kidney cells.

Immunohistochemistry-Paraffin: GPR137B Antibody [NLS788] - Analysis of anti-GPR137B / TM7SF1 antibody with human brain at 6 ug/ml.

Immunohistochemistry-Paraffin: GPR137B Antibody [NLS788] - Anti-GPR137B antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: GPR137B Antibody [NLS788] - Anti-GPR137B antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: GPR137B Antibody [NLS788] - Brain, cortex, neurons

Product Discontinued

GPR137B Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human GPR137B / TM7SF1.
• Specificity: Human GPR137B / TM7SF1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Goat (94%), Turkey (100%), Xenopus (94%), Zebrafish (94%), Opossum (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR137B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 6-12 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 6-12 ug/ml

Reactivity Notes

Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephnat (100%), Lizard (100%), Panda (94%), Platypus (88%), Stickleback (88%), Pufferfish (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR137B Antibody

• G protein-coupled receptor 137B
• TM7SF1
• transmembrane 7 superfamily member 1 (upregulated in kidney)

Background

GPR137B is an Orphan-U GPCR with an unknown ligand. This receptor has been shown to be upregulated during kidney development. GPR137B has been reported to be expressed in adult kidney and heart, but not in fetal kidney. ESTs have been isolated from a wide variety of tissues, including B-cell/lung/testis, brain, connective tissue, ear, embryo, eye, gall bladder, kidney, liver/spleen, lung, melanocyte/uterus/fetal heart, nerve, pineal, placenta, skin, spleen, testis, tonsil, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GPR137B Antibody (NLS788)(1)

Publication using NLS788

• Elbadawy M, Yamanaka M, Goto Y et al. Efficacy of primary liver organoid culture from different stages of non-alcoholic steatohepatitis (NASH) mouse model Biomaterials 2020-01-01 [PMID: 32044522] (ICC/IF, Mouse)

Bioinformatics

• Gene Symbol: GPR137B
• Entrez:
  • 7107(Human)
• Uniprot:
  • O60478(Human)