GNB2 Antibody (S04-1A2)

Western Blot: GNB2 Antibody (S04-1A2) [NBP3-19495] - Western blot detection of GNB2 in Rat Brain, C6, 3T3, Hela cell lysates using NBP3-19495 (1:1000 diluted). Predicted band size: 37kDa. Observed band size: 32kDa.

Immunohistochemistry-Paraffin: GNB2 Antibody (S04-1A2) [NBP3-19495] - Immunohistochemistry of GNB2 in paraffin-embedded Human Cholangiocarcinoma using NBP3-19495 at dilution 1/20

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: S04-1A2
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

GNB2 Antibody (S04-1A2) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human GNB2 (Uniprot # P62879)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GNB2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1/20
  • Immunohistochemistry-Paraffin
  • Western Blot 1/1000-1/5000
• Theoretical MW: 32 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for GNB2 Antibody (S04-1A2)

• beta-2 subunit
• guanine nucleotide binding protein (G protein), beta polypeptide 2
• guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2
• guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
• signal-transducing guanine nucleotide-binding regulatory protein beta subunit

Background

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNB2