GIRK2 Antibody (KCNJ6/7559) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: IHC
• Clone: KCNJ6/7559
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

GIRK2 Antibody (KCNJ6/7559) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: Recombinant fragment of human GIRK2 protein (exact sequence is proprietary)
• Localization: Membrane.
• Isotype: IgG2 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KCNJ6
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for GIRK2 Antibody (KCNJ6/7559) [CoraFluor™ 1]

• BIR1
• BIR1Kir3.2
• G protein-activated inward rectifier potassium channel 2
• GIRK2
• GIRK-2
• GIRK2KATP-2
• hiGIRK2
• Inward rectifier K(+) channel Kir3.2
• inward rectifier potassium channel KIR3.2
• KATP2
• KATP-2
• KATP2human G protein coupled inward rectifier potassium channel 2 (hiGIRK2)10KCNJ7KIR3.2
• KCNJ6
• KCNJ7
• MGC126596
• Potassium channel, inwardly rectifying subfamily J member 6
• potassium inwardly-rectifying channel, subfamily J, member 6

Background

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNJ6