WB: Approx. 38 kDa band and strong 23-24 kDa band bands observed in lysates of HeLa, and approx. 24 kDa band also observed in human pancreas, kidney and muscle lysates (calculated MW of 36.0 kDa band according to NP_005707.1, NP_974197.1 and NP_974199.1 and 26.1 kDa band according to NP_974198.1 and NP_974223.1). In transfected HEK293 transiently expressing GIPC1 isoform 1 a band of approx. 40 kDa is observed. This band is not observed in the non-transfected HEK293.
36 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for GIPC1 Antibody
C19orf3chromosome 19 open reading frame 3
GAIP C-terminus-interacting protein
GIPC PDZ domain containing family, member 1
GLUT1 C-terminal binding protein
IGF-1 receptor interacting protein 1
PDZ domain-containing protein GIPC1
regulator of G-protein signalling 19 interacting protein 1
Tax interaction protein 2
TIP-2RGS19-interacting protein 1
GIPC1, GIPC2, and GIPC3 are a family of central PDZ-domain proteins with GH1 and GH2 domains. GIPC1 has been shown to be highly expressed in gastric, pancreatic, colorectal and lung cancer cell lines. It also has a list of identified binding partners in vitro including many transmembrane proteins and cell surface molecules involved in adhesion. In vivo, there is evidence that suggests a role of GIPC1 in transmembrane protein trafficking through the Golgi stacks and possibly a role in the later stages of vesicle trafficking.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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