GIPC1 Antibody (24GB6645)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Mycoplasma
• Clone: 24GB6645
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

GIPC1 Antibody (24GB6645) Summary

• Description: Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
• Immunogen: Recombinant protein of human GIPC1 (Uniprot: O14908)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GIPC1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for GIPC1 Antibody (24GB6645)

• C19orf3chromosome 19 open reading frame 3
• GAIP C-terminus-interacting protein
• GIPC PDZ domain containing family, member 1
• GIPCRGS-GAIP-interacting protein
• GLUT1 C-terminal binding protein
• GLUT1CBP
• IGF-1 receptor interacting protein 1
• MGC15889
• MGC3774
• NIP
• PDZ domain-containing protein GIPC1
• regulator of G-protein signalling 19 interacting protein 1
• RGS19IP1IIP-1
• SEMCAP
• SYNECTIIN
• SYNECTIN
• Tax interaction protein 2
• TIP-2RGS19-interacting protein 1

Background

GIPC1, GIPC2, and GIPC3 are a family of central PDZ-domain proteins with GH1 and GH2 domains. GIPC1 has been shown to be highly expressed in gastric, pancreatic, colorectal and lung cancer cell lines. It also has a list of identified binding partners in vitro including many transmembrane proteins and cell surface molecules involved in adhesion. In vivo, there is evidence that suggests a role of GIPC1 in transmembrane protein trafficking through the Golgi stacks and possibly a role in the later stages of vesicle trafficking.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GIPC1