GGA2 Antibody

Product Discontinued

GGA2 Antibody Summary

• Immunogen: A synthetic peptide from the GAT domain of mouse GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.
• Localization: subcellular location: golgi apparatus, trans-golgi network membrane; peripheral membrane protein. endosome membrane; peripheral membrane protein.
• Specificity: GGA2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GGA2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 10-50 ug/ml

Reactivity Notes

Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: IgG purified
• Reconstitution Instructions: Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for GGA2 Antibody

• FLJ20966
• Gamma-adaptin-related protein 2
• golgi associated, gamma adaptin ear containing, ARF binding protein 2
• golgi-associated, gamma adaptin ear containing, ARF binding protein 2
• Golgi-localized, gamma ear-containing, ARF-binding protein 2
• KIAA1080ADP-ribosylation factor-binding protein GGA2
• VEAR
• VHS domain and ear domain of gamma-adaptin
• VHS domain and ear domain-containing protein

Background

GGA2 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain that mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GGA2
• Entrez:
  • 74105(Mouse)
  • 293455(Rat)
• Uniprot:
  • Q6P5E6(Mouse)