GGA1 Antibody (3F11)

Western Blot: GGA1 Antibody (3F11) [H00026088-M01] - GGA1 monoclonal antibody (M01), clone 3F11 Analysis of GGA1 expression in K-562.

Immunohistochemistry-Paraffin: GGA1 Antibody (3F11) [H00026088-M01] - Analysis of monoclonal antibody to GGA1 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.

ELISA: GGA1 Antibody (3F11) [H00026088-M01] - Detection limit for recombinant GST tagged GGA1 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: 3F11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

GGA1 Antibody (3F11) Summary

• Immunogen: GGA1 (AAH29388, 1 a.a. ~ 89 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALTVRRGEATIRPPPCDDTKGGQD
• Specificity: GGA1 - golgi associated, gamma adaptin ear containing, ARF binding protein 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GGA1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GGA1 Antibody (3F11)

• ADP-ribosylation factor binding protein 1
• ADP-ribosylation factor-binding protein GGA1
• gamma adaptin ear containing, ARF binding protein 1
• gamma-adaptin related protein 1
• Gamma-adaptin-related protein 1
• golgi-associated, gamma adaptin ear containing, ARF binding protein 1
• Golgi-localized, gamma ear-containing, ARF-binding protein 1

Background

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GGA1 Antibody (H00026088-M01)(1)

Publication using H00026088-M01

• Ye SB, Cheng YK, Li PS et al. High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer NPJ precision oncology 2023-05-31 [PMID: 37258779] (MI, Human)

Bioinformatics

• Gene Symbol: GGA1
• Entrez:
  • 26088(Human)
• OMIM:
  • 606004(Human)
• Uniprot:
  • AAH29388(Human)