GAK Antibody [HRP]

• Reactivity: Hu, Mu
• Applications: WB, IP (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: HRP

GAK Antibody [HRP] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 675 to 725 of human Cyclin G Associated Kinase using the numbering given in entry NP_005246.2 (GeneID 2580).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GAK
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for GAK Antibody [HRP]

• Auxillin 2
• cyclin G associated kinase
• cyclin-G-associated kinase
• EC 2.7.11.1
• FLJ16629
• FLJ40395
• GAK
• MGC99654

Background

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GAK