GABA-B R1 Antibody

Product Discontinued

GABA-B R1 Antibody Summary

• Immunogen: Synthetic peptide to GABA BR1
• Specificity: This is specific for GABA BR1 protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABBR1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Application Notes: NB 300-145 can be used for western blotting where it recognizes a band at 108 kDa representing GABABR1 protein. Suggested working dilutions: * Western Blot 1:500-1:1,000 Immunohistochemistry ND Immunoprecipitation ND *The investigator should determine the optimal working dilution for a specific application. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 100 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Human Brain Cerebral Cortex Whole Tissue Lysate (Adult Whole Normal)
  Human Brain Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: 0.02% Sodium Azide
• Purity: Unpurified

Alternate Names for GABA-B R1 Antibody

• FLJ92613
• GABA B R1
• GABABR1
• GABBR1
• GABBR1-3
• gamma-aminobutyric acid (GABA) B receptor, 1
• gamma-aminobutyric acid type B receptor subunit 1
• Gb1
• GPRC3A
• GPRC3Asubunit 1c
• hGB1a
• seven transmembrane helix receptor

Background

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA A and GABA C receptors and GABA B, the latter of which acts through a G protein mechanism. GABA BR1 is one of the two G-protein coupled receptors for GABA B that acts as a heteromeric assembly with GABA BR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GABBR1
• Entrez:
  • 2550(Human)