GABA-AR alpha 1 Antibody

Product Discontinued

GABA-AR alpha 1 Antibody Summary

• Immunogen: Fusion protein (Rat) consisting of MBP and cytoplasmic loop sequence of the GABA-A receptor alpha 1 subunit.
• Localization: Membrane; multi pass membrane protein.
• Specificity: This reacts with the 51 kDa alpha 1 subunit of rat brain GABA A. There is no known reactivity with other GABA subunits. There is no homology with other GABA subunits.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABRA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: IP: Use 15 ug (59% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains). WB: Use at a dilution of 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 55 kDa). Not tested in other applications.Optimal dilutions/conc

Reactivity Notes

Cross-reacts with Rat.Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 10mM HEPES (pH7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for GABA-AR alpha 1 Antibody

• ECA4
• EJM
• EJM5GABA(A) receptor subunit alpha-1
• GABA A R alpha 1
• GABAAR alpha 1
• GABAARa1
• GABRA1
• gamma-aminobutyric acid (GABA) A receptor, alpha 1
• gamma-aminobutyric acid receptor subunit alpha-1

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GABRA1
• Entrez:
  • 2554(Human)
  • 29705(Rat)