Recombinant Human G3BP2 His Protein

SDS-Page: Recombinant Human G3BP2 His Protein [NBP1-78843] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human G3BP2 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-449 of Human G3BP2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVMEKP SPLLVGREFV RQYYTLLNKA PEYLHRFYGR NSSYVHGGVD ASGKPQEAVY GQNDIHHKVL SLNFSECHTK IRHVDAHATL SDGVVVQVMG LLSNSGQPER KFMQTFVLAP EGSVPNKFYV HNDMFRYEDE VFGDSEPELD EESEDEVEEE QEERQPSPEP VQENANSGYY EAHPVTNGIE EPLEESSHEP EPEPESETKT EELKPQVEEK NLEELEEKST TPPPAEPVSL PQEPPKPRVE AKPEVQSQPP RVREQRPRER PGFPPRGPRP GRGDMEQNDS DNRRIIRYPD SHQLFVGNLP HDIDENELKE FFMSFGNVVE LRINTKGVGG KLPNFGFVVF DDSEPVQRIL IAKPIMFRGE VRLNVEEKKT RAARERETRG GGDDRRDIRR NDRGPGGPRG IVGGGMMRDR DGRGPPPRGG MAQKLGSGRG TGQMEGRFTG QRR

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: G3BP2
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 53.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.2 M NaCl, 2 mM DTT, 0.1 mM PMSF
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human G3BP2 His Protein

• G3BP-2
• GAP SH3 domain-binding protein 2
• GTPase activating protein (SH3 domain) binding protein 2
• KIAA0660
• ras GTPase-activating protein-binding protein 2
• Ras-GTPase activating protein SH3 domain-binding protein 2

Background

G3BP2, also known as ras GTPase-activating protein-binding protein 2, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein probably is scaffold protein that may be involved in mRNA transport. Recombinant human G3BP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for G3BP2 Protein (NBP1-78843)(2)

Publications using NBP1-78843

• Wang C, Terrigno M, Li J et al. Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation Neuron 2023-06-23 [PMID: 37385246]
• Sanders DW, Kedersha N, Lee DSW et al. Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization Cell 2020-04-16 [PMID: 32302570] (WB)

Bioinformatics

• Gene Symbol: G3BP2