Recombinant Human FXYD5/Dysadherin His Protein

SDS-Page: Recombinant Human FXYD5/Dysadherin Protein [NBP2-23064]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human FXYD5/Dysadherin His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 22-145 of Human FXYD5/Dysadherin
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSQTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: FXYD5
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 16.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human FXYD5/Dysadherin His Protein

• DYSAD
• Dysadherin
• EF-8
• FXYD domain containing ion transport regulator 5
• FXYD domain-containing ion transport regulator 5
• FXYD5
• IWU1
• KCT1
• keratinocytes associated transmembrane protein 1
• OIT2
• PRO6241
• RIC

Background

FXYD domain-containing ion transport regulator 5, also known as FXYD5, is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. FXYD5 is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis tissue, and maps to human chromosome 19q13.2. Recombinant human FXYD5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: FXYD5