Frizzled-6 Antibody

Images

 
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with transfection control at 6 ug/ ml.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with transfection control.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with transfected cells expressing Frizzled-6 at 6 ug/ ml.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with human pancreas.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mk, Pm, Mu, Po, Bv, Ca, Eq, RbSpecies Glossary
Applications IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Frizzled-6 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.
Specificity
Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD3 (50%).
Predicted Species
Mouse (94%), Porcine (94%), Equine (94%), Canine (94%), Rabbit (94%), Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FZD6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 6 - 14 ug/ml
  • Immunocytochemistry 3 - 6 ug/ml

Reactivity Notes

Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Panda (94%), Rat (88%), Opossum (88%), Turkey (88%), Chicken (88%), Elephant (81%), Bat (81%), Lizard (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Frizzled-6 Antibody

  • frizzled (Drosophila) homolog 6
  • frizzled homolog 6 (Drosophila)
  • Frizzled6
  • Frizzled-6
  • FZ6
  • fz-6
  • FZD6
  • Hfz6
  • seven transmembrane helix receptor

Background

FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled. FZD6 expression has been reported in brain, colon, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, testis, and thymus. Various tumor cell lines have also been shown to express FZD6. ESTs have been isolated from blood, brain, breast, connective tissue, liver, liver/spleen, lung, placenta, testis, thyroid, and vessel libraries. In addition, several ESTs have been isolated from tumor libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FZD6
Entrez