FOLR2 Antibody (583121) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 583121
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

FOLR2 Antibody (583121) [Alexa Fluor® 532] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human FOLR2
  Gln22-His228
  Accession # P14207
• Specificity: Detects human FOLR2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FOLR1, 3, 4, or recombinant mouse FOLR2 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FOLR2 Antibody (583121) [Alexa Fluor® 532]

• beta-HFR
• FBP
• FBP/PL-1
• folate receptor 2 (fetal)
• Folate receptor 2
• folate receptor beta
• folate receptor, beta
• Folate receptor, fetal/placental
• folate-binding protein, fetal/placental
• FOLR2
• FR-beta
• FR-P3
• Placental folate-binding protein

Background

Folate Receptor 2 (FOLR2), also known as Folate Receptor beta, is a 38 kDa glycoprotein that is anchored to the membrane via glycosyl phosphatidylinositol. It mediates the cellular uptake of dietary folates that are required for key steps in amino acid metabolism. FOLR2 is predominantly expressed in placenta, myeloid cells, and some CD34⁺ hematopoietic progenitor cells. It is upregulated on some cancer cells and at sites of chronic inflammation. Human FOLR2 shares 83% amino acid sequence identity with mouse and rat FOLR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P14207(Human)