FOLR2 Antibody (583121) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 583121
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

FOLR2 Antibody (583121) [Alexa Fluor® 750] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human FOLR2
  Gln22-His228
  Accession # P14207
• Specificity: Detects human FOLR2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FOLR1, 3, 4, or recombinant mouse FOLR2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FOLR2 Antibody (583121) [Alexa Fluor® 750]

• beta-HFR
• FBP
• FBP/PL-1
• folate receptor 2 (fetal)
• Folate receptor 2
• folate receptor beta
• folate receptor, beta
• Folate receptor, fetal/placental
• folate-binding protein, fetal/placental
• FOLR2
• FR-beta
• FR-P3
• Placental folate-binding protein

Background

Folate Receptor 2 (FOLR2), also known as Folate Receptor beta, is a 38 kDa glycoprotein that is anchored to the membrane via glycosyl phosphatidylinositol. It mediates the cellular uptake of dietary folates that are required for key steps in amino acid metabolism. FOLR2 is predominantly expressed in placenta, myeloid cells, and some CD34⁺ hematopoietic progenitor cells. It is upregulated on some cancer cells and at sites of chronic inflammation. Human FOLR2 shares 83% amino acid sequence identity with mouse and rat FOLR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.