FOG2 Antibody

Immunocytochemistry/Immunofluorescence: FOG2 Antibody [NBP1-91909] - Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: FOG2 Antibody [NBP1-91909] - Staining of human skin shows moderate nuclear positivity in squamous epithelial cells.

Immunohistochemistry-Paraffin: FOG2 Antibody [NBP1-91909] - Staining of human cerebral cortex shows strong nuclear postivity in neuronal cells.

Immunohistochemistry-Paraffin: FOG2 Antibody [NBP1-91909] - Staining of human lung shows strong nuclear postivity in pneumocytes.

Immunohistochemistry-Paraffin: FOG2 Antibody [NBP1-91909] - Staining of human breast shows moderate nuclear positivity in glandular cells.

Product Discontinued

FOG2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: CLPEQEQRPPLVQQRFLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSKCDTTHSSVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQ
• Predicted Species: Mouse (95%), Rat (96%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZFPM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  FOG2 Protein (NBP1-91909PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for FOG2 Antibody

• transcription factor GATA4, modulator of
• zinc finger protein 89B
• zinc finger protein, multitype 2

Background

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZFPM2