Western Blot: FKBP5/FKBP51 Antibody [NB100-68240] - Western Blot and Immunoprecipitation: FKBP5/FKBP51 Antibody NB100-68240 - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T ...read more
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody [NB100-68240] - Human prostate carcinoma. Antibody used at a dilution of 1:1,000.
Immunohistochemistry-Paraffin: FKBP5/FKBP51 Antibody [NB100-68240] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-FKBP5/FKBP51 used at a dilution of 1:500.
The immunogen recognized by this antibody maps to a region between residue 407 and 457 of human FK506 binding protein 5 (51 kDa FK506-binding protein) using the numbering given in entry NP_004108.1 (GeneID 2289).
Monkey (100%), Primate (100%)
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Immunohistochemistry 1:200 to 1:1,000. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NB100-68240 in the following applications:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.