FIP1L1 Antibody

Images

 
Western Blot: FIP1L1 Antibody [NB100-74588] - Detection of Human FIP1 on HeLa whole cell lysate using NB100-74588. FIP1 was also immunoprecipitated by rabbit anti-FIP1 antibody NB100-74589.
Immunohistochemistry: FIP1L1 Antibody [NB100-74588] - Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-FIP1 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

FIP1L1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human factor interacting with PAP using the numbering given in entry NP_112179.2 (GeneID 81608).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FIP1L1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry-Paraffin 1:500-1:2000
  • Immunoprecipitation 2-5 ug/mg
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FIP1L1 Antibody

  • DKFZp586K0717
  • EC 1.1.1.86
  • EC 4.2.1.33
  • Factor interacting with PAP
  • FIP1 like 1 (S. cerevisiae)
  • FIP1
  • FIP1-like 1 protein
  • FLJ33619
  • hFip1
  • pre-mRNA 3'-end-processing factor FIP1
  • Rearranged in hypereosinophilia
  • Rhe

Background

FIP1 was originally identified as Rhe (rearranged in hypereosinophilia) and part of a fusion protein encoded by a genetic rearrangement between the N-terminal region of FIP1 (Rhe) and the C-terminal region of the platelet-derived growth factor receptor alpha (PDGFRalpha). The fusion protein exhibits aberrant tyrosine kinase activity and is associated with hypereosinophilic syndrome (HES); a rare hematologic disorder characterized by an overproduction of eosinophils that results in organ damage. FIP1 was also identified as FIP1-like 1 in a database search for a human homolog of the yeast Fip1p (factor interacting with PAP), a subunit of the yeast 3'-end processing complex, CPF (cleavage and polyadenylation factor). Human FIP1 was similarly found to interact with PAP and CPSF160 as part of the human CPSF (cleavage and polyadenylation specificity factor) complex. In association with CPSF160, FIP1 is able to recognize U-rich elements on pre-mRNA and stimulate PAP activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF1062
Species: Mu
Applications: WB, IHC, Neut
NBP1-69668
Species: Hu
Applications: WB
NBP2-07087
Species: Hu
AF5414
Species: Hu
Applications: WB, Simple Western
AF1356
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready
NBP2-11538
Species: Hu, Mu, Rt
Applications: WB, IHC-P
NBP2-49154
Species: Hu
Applications: IHC
AF385
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready, Neut
AF2988
Species: Mu, Rt
Applications: WB
NBP2-24763
Species: Hu, Pm
Applications: WB, IHC-P
NBP2-38621
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB600-1287
Species: Hu, Mu, Rt
Applications: WB, Flow, IP, CyTOF-ready
NBP2-24915
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC-P
NBP1-32719
Species: Hu
Applications: WB, ICC/IF

Publications for FIP1L1 Antibody (NB100-74588) (0)

There are no publications for FIP1L1 Antibody (NB100-74588).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for FIP1L1 Antibody (NB100-74588) (0)

There are no reviews for FIP1L1 Antibody (NB100-74588). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for FIP1L1 Antibody (NB100-74588) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional FIP1L1 Products

Bioinformatics Tool for FIP1L1 Antibody (NB100-74588)

Discover related pathways, diseases and genes to FIP1L1 Antibody (NB100-74588). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for FIP1L1 Antibody (NB100-74588)

Discover more about diseases related to FIP1L1 Antibody (NB100-74588).
 

Pathways for FIP1L1 Antibody (NB100-74588)

View related products by pathway.

PTMs for FIP1L1 Antibody (NB100-74588)

Learn more about PTMs related to FIP1L1 Antibody (NB100-74588).

Blogs on FIP1L1

There are no specific blogs for FIP1L1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our FIP1L1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol FIP1L1
Entrez
Uniprot