FIP1L1 Antibody


Western Blot: FIP1L1 Antibody [NB100-74588] - Detection of Human FIP1 on HeLa whole cell lysate using NB100-74588. FIP1 was also immunoprecipitated by rabbit anti-FIP1 antibody NB100-74589.
Immunohistochemistry-Paraffin: FIP1L1 Antibody [NB100-74588] - Human pancreatic islet cell tumor. Antibody used at a dilution of 1:1,000.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, IP
1.0 mg/ml

Order Details

FIP1L1 Antibody Summary

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human factor interacting with PAP using the numbering given in entry NP_112179.2 (GeneID 81608).
Predicted Species
Bovine (100%), Monkey (100%), Primate (100%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate buffer, pH 7 to 8
0.09% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset, African elephant, Gray short-tailed opossum, Small-eared galago, Thirteen-lined ground squirrel and Northern white-cheeked gibbon.

Alternate Names for FIP1L1 Antibody

  • DKFZp586K0717
  • EC
  • EC
  • Factor interacting with PAP
  • FIP1 like 1 (S. cerevisiae)
  • FIP1
  • FIP1-like 1 protein
  • FLJ33619
  • hFip1
  • pre-mRNA 3'-end-processing factor FIP1
  • Rearranged in hypereosinophilia
  • Rhe


FIP1 was originally identified as Rhe (rearranged in hypereosinophilia) and part of a fusion protein encoded by a genetic rearrangement between the N-terminal region of FIP1 (Rhe) and the C-terminal region of the platelet-derived growth factor receptor alpha (PDGFRalpha). The fusion protein exhibits aberrant tyrosine kinase activity and is associated with hypereosinophilic syndrome (HES); a rare hematologic disorder characterized by an overproduction of eosinophils that results in organ damage. FIP1 was also identified as FIP1-like 1 in a database search for a human homolog of the yeast Fip1p (factor interacting with PAP), a subunit of the yeast 3'-end processing complex, CPF (cleavage and polyadenylation factor). Human FIP1 was similarly found to interact with PAP and CPSF160 as part of the human CPSF (cleavage and polyadenylation specificity factor) complex. In association with CPSF160, FIP1 is able to recognize U-rich elements on pre-mRNA and stimulate PAP activity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol FIP1L1

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