Filamin B Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, CaSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Filamin B Antibody Summary

Immunogen
Peptide with sequence KITDDSRRCSQVK corresponding to internal region according to NP_001157789.1, NP_001157790.1, NP_001157791.1.
Specificity
This antibody is expected to recognise all reported isoforms (NP_001448.2; NP_001157789.1; NP_001157790.1; NP_001157791.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
FLNB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Preliminary experiments in human brain, mouse brain and rat brain lysates gave no specific signal but low background.
Publications
Read Publication using NB100-53813.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Filamin B Antibody

  • ABP-278filamin B, beta (actin binding protein 278)
  • ABP-280 homolog
  • actin binding protein 278
  • Actin-binding-like protein
  • AOI
  • beta-filamin
  • DKFZp686O033
  • FH1
  • filamin B, beta
  • Filamin homolog 1
  • filamin-3
  • filamin-B
  • FLN1L
  • FLN3
  • FLN-B
  • Larsen syndrome 1 (autosomal dominant)
  • LRS1
  • SCT
  • TABPABP-280
  • TAPDKFZp686A1668
  • Thyroid autoantigen
  • Truncated ABP
  • Truncated actin-binding protein

Background

FLNB connects cell membrane constituents to the actin cytoskeleton. It may promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. It anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Filamin B Antibody (NB100-53813)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FLNB
Entrez
Uniprot