Filamin B Antibody

ELISA: Filamin B Antibody [36240002]

Product Discontinued

Filamin B Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human FLNB.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FLNB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Filamin B Antibody

• ABP-278filamin B, beta (actin binding protein 278)
• ABP-280 homolog
• actin binding protein 278
• Actin-binding-like protein
• AOI
• beta-filamin
• DKFZp686O033
• FH1
• filamin B, beta
• Filamin homolog 1
• filamin-3
• filamin-B
• FLN1L
• FLN3
• FLN-B
• Larsen syndrome 1 (autosomal dominant)
• LRS1
• SCT
• TABPABP-280
• TAPDKFZp686A1668
• Thyroid autoantigen
• Truncated ABP
• Truncated actin-binding protein

Background

FLNB connects cell membrane constituents to the actin cytoskeleton. It may promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. It anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Filamin B Antibody (36240002)(2)

Publications using 36240002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

FAQs for Filamin B Antibody (36240002). (Showing 1 - 1 of 1 FAQs).

1. Would you please provide the exact immunogen sequence of 36240002 if the information is not proprietary?
   • The amino acid range of the immunogen for 36240002 is from 1656-1815aa.

Bioinformatics

• Gene Symbol: FLNB
• Entrez:
  • 2317(Human)
• Uniprot:
  • O75369(Human)