FGF-22 Antibody [DyLight 350]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 350

FGF-22 Antibody [DyLight 350] Summary

• Immunogen: E. coli-derived recombinant human FGF-22
  Thr23-Ser170
  Accession # Q9HCT0
• Specificity: Detects human FGF-22 in direct ELISAs and Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) FGF-2, -3, -4, -5, -6, -7, -8b, -9, -10, -11, -12, -13, -16, -17, -18, -19, -20, -23, and recombinant mouse (rm) FGF-8, rmFGF-15, and rhFGF‑acidic is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: FGF22
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for FGF-22 Antibody [DyLight 350]

• FGF22
• FGF-22
• fibroblast growth factor 22

Background

Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. Fibroblast growth factor- 22 (FGF-22) is a secreted protein whose gene is localized to human chromosome 19p13.3. FGF-22 is expressed preferentially in the inner root sheath of the hair follicle, suggesting that it is important in hair development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FGF22