Fc epsilon RI Products

Antibodies
Fc epsilon RI Antibody (1F2A9 ...
Fc epsilon RI Antibody (1F2A9)
NBP2-37402
Species: Hu
Applications: WB, ELISA, Flow, CyTOF-ready
Host: Mouse Monoclonal
Lysates
Fc epsilon RI Overexpression ...
Fc epsilon RI Overexpression Lysat...
NBL1-10650
Applications: WB
Fc epsilon RI Overexpression ...
Fc epsilon RI Overexpression Lysat...
H00002205-T02
Species: Hu
Applications: WB
Proteins
Fc epsilon RI Recombinant Pro ...
Fc epsilon RI Recombinant Protein ...
NBP2-54974PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human Fc epsilon ...
Recombinant Human Fc epsilon RI Pr...
NBP2-23043
Species: Hu
Applications: PAGE
RNAi
Fc epsilon RI RNAi
Fc epsilon RI RNAi
H00002205-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Fc epsilon RI RNAi
Fc epsilon RI RNAi
H00002205-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The allergic reaction is mediated through the IgE high affinity receptor (FceRI). When a multivalent antigen is presented, a redistribution of the monomeric IgE FceRI receptor complexes cause the degranulation of mast cells and basophils, resulting in the subsequent release of factors responsible for the allergic reaction. The FceRI receptor is a tetrameric complex, consisting of a a-chain, b-chain and a dimeric g-chain. While the a-chain is primarily involved with the binding of IgE, the signal is transferred through the g subunit, which contains the immunoreceptor tyrosine activation motifs (ITAM) critical for initiating receptor mediated signal transduction through the Syk and Lyn tyrosine kinases. The FceRI receptor is able to engage and disengage the IgE, providing a versatile model for studying the function of kinase coupled receptors.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 2205
Alternate Names
  • high-affinity, of mast cells, alpha polypeptide
  • high affinity immunoglobulin epsilon receptor subunit alpha
  • Fc-epsilon RI-alpha
  • high affinity immunoglobulin epsilon receptor alpha-subunit
  • FcERI
  • alpha polypeptide
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

Research Areas for Fc epsilon RI

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Asthma
Cancer
Immunology
Signal Transduction

PTMs for Fc epsilon RI

Learn more about PTMs related to Fc epsilon RI.

Biotinylation
Citrullination

Bioinformatics Tool for Fc epsilon RI

Discover related pathways, diseases and genes to Fc epsilon RI. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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