FBXO45 Antibody (RB53750)

• Reactivity: Hu
• Applications: WB
• Clone: RB53750
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

FBXO45 Antibody (RB53750) Summary

• Immunogen: This FBXO45 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 83-115 amino acids from human FBXO45.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FBXO45
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for FBXO45 Antibody (RB53750)

• F-box only protein 45
• F-box protein 45
• F-box/SPRY domain-containing protein 1
• Fbx45

Background

F-box/SPRY domain-containing protein 1, also known as F-box only protein 45 and FBXO45, is a component of the E3 ubiquitin ligase complex. FBXO45 is required for normal neuromuscular synaptogenesis, neuronal migration and axon pathfinding. FBXO45 also plays a role in regulating neurotransmission by mature neurons and controlling synaptic activity via UNC13A in the ubiquitin dependent pathway. FBXO45 protein recognizes TP73 and promotes it ubiquitination and degradation. FBXO45 expression is down regulated in response to DNA damage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FBXO45