FBXO45 Products

Antibodies
FBXO45 Antibody
FBXO45 Antibody
NBP1-91891
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
FBXO45 Partial Recombinant Pr ...
FBXO45 Partial Recombinant Protein
H00200933-Q01
Species: Hu
Applications: WB, ELISA, PA
FBXO45 Recombinant Protein An ...
FBXO45 Recombinant Protein Antigen
NBP1-91891PEP
Species: Hu
Applications: AC

Description

F-box/SPRY domain-containing protein 1, also known as F-box only protein 45 and FBXO45, is a component of the E3 ubiquitin ligase complex. FBXO45 is required for normal neuromuscular synaptogenesis, neuronal migration and axon pathfinding. FBXO45 also plays a role in regulating neurotransmission by mature neurons and controlling synaptic activity via UNC13A in the ubiquitin dependent pathway. FBXO45 protein recognizes TP73 and promotes it ubiquitination and degradation. FBXO45 expression is down regulated in response to DNA damage.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 200933
Alternate Names
  • F-box/SPRY domain-containing protein 1
  • FBX45
  • F-box only protein 45
  • Fbx45
  • F-box protein 45

Pathways for FBXO45

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Cell Death
Innervation

PTMs for FBXO45

Learn more about PTMs related to FBXO45.

Ubiquitination
Phosphorylation
Acetylation

Bioinformatics Tool for FBXO45

Discover related pathways, diseases and genes to FBXO45. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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