FABP3/H-FABP Antibody (9F3)

Product Discontinued

FABP3/H-FABP Antibody (9F3) Summary

• Immunogen: Human fatty acid binding protein (FABP).
• Marker: Cardiac Marker
• Specificity: Human fatty acid binding protein. Specific titer is 10^6
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FABP3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunoassay
  • Sandwich ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: We recommend using following pairs of antibodies for sandwich immunoassay (capture-detection): NB110-57588 - NB120-8315

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for FABP3/H-FABP Antibody (9F3)

• FABP11
• FABP3
• fatty acid binding protein 11
• fatty acid binding protein 3, muscle and heart (mammary-derived growthinhibitor)
• Fatty acid-binding protein 3
• Fatty acid-binding protein 3, muscle
• fatty acid-binding protein, heart
• Heart-type fatty acid-binding protein
• HFABP
• H-FABP
• H-FABPM-FABP
• Mammary-derived growth inhibitor
• MDGI
• Muscle fatty acid-binding protein
• O-FABP

Background

Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellulair utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of ischemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FABP3
• Entrez:
  • 2170(Human)