ERManI Antibody (3C2) [HRP]

Images

 
There are currently no images for ERManI Antibody (NBP2-13167H).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu(-)Species Glossary
Applications WB, ELISA, IHC, IHC-P
Clone
3C2
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

ERManI Antibody (3C2) [HRP] Summary

Immunogen
Full length human recombinant ERManI [Swiss-Prot# Q9UKM7]
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MAN1B1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This ERManI Antibody (3C2) is useful for Immunocytochemistry/Immunofluorescence, Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry on paraffin embedded sections. In ICC/IF, endoplasmic reticulum membrane staining was observed in HeLa cells. In Western Blot, a band is seen ~90 kDa representing ERManI. In IHC-P, staining was observed in the endoplasmic reticulum of human breast cancer tissue. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Readout System

Reactivity Notes

Human. Does not cross react with mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ERManI Antibody (3C2) [HRP]

  • alpha 1,2-mannosidase
  • EC 3.2.1.113
  • endoplasmic reticulum alpha-mannosidase 1
  • endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
  • endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
  • ER alpha 1,2-mannosidase
  • ER alpha-1,2-mannosidase
  • ER ManI
  • ER mannosidase 1
  • ERMan1
  • Man9GlcNAc2-specific processing alpha-mannosidase
  • Man9GlcNAc2-specific-processing alpha-mannosidase
  • MANA-ER
  • Mannosidase alpha class 1B member 1
  • mannosidase, alpha, class 1B, member 1
  • MRT15
  • RP11-350O14.2

Background

ERManI, also known as endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase or MAN1B1, is a putative ER resident mannosidase that plays a rate-limiting role in generating a signal that targets misfolded N-linked glycoproteins for ER-associated degradation (ERAD). ERManI codes for an enzyme that converts Man9GlcNAc to Man8GlcNAc isomer B during N-glycan biosynthesis. It also facilitates the trimming of Man5-6GlcNAc2 in the endoplasmic reticulum associated degradation pathway. Multiple transcript variants of ERManI can result from alternative splicing, and a related pseudogene can be found on chromosome 11. Research has found that mutations on the ERManI gene can result in autosomal-recessive intellectual disabilities and developmental delays (PMID: 21763484). ERManI is predominately localized to the Golgi and endoplasmic reticulum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-45897
Species: Hu
Applications: WB, IHC
NBP1-32108
Species: Hu, Rt
Applications: WB, ICC/IF
NBP2-24916
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
NBP1-78159
Species: Hu, Rt, Po, Bv
Applications: WB, EM, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vitro, RIA
NBP2-29940
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC-P
NBP2-16861
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-20799
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-19010
Species: Hu
Applications: WB, IHC, IHC-P
NB110-94158
Species: Hu, Mu, Rt, Bv, Pm
Applications: WB, ICC/IF
H00001717-D01P
Species: Hu, Mu, Rt
Applications: WB
NBP1-86692
Species: Hu
Applications: ICC/IF, IHC, IHC-P
H00002027-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P, RNAi
NBP1-89158
Species: Hu
Applications: WB, Simple Western, IHC, IHC-P
NBP1-91658
Species: Hu
Applications: WB, IHC, IHC-P
H00027161-M01
Species: Hu, Mu, Rt
Applications: WB, ChIP, ELISA, ICC/IF, IHC, IHC-P, IP, RNAi
NBP1-89227
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-84570
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-24589
Species: Hu, Mu, Rt, Bv, Eq, Pm
Applications: WB, IHC-P
AF4094
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
NBP2-13167H
Species: Hu, Mu(-)
Applications: WB, ELISA, IHC, IHC-P

Publications for ERManI Antibody (NBP2-13167H) (0)

There are no publications for ERManI Antibody (NBP2-13167H).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for ERManI Antibody (NBP2-13167H) (0)

There are no reviews for ERManI Antibody (NBP2-13167H). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for ERManI Antibody (NBP2-13167H) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NBP2-13167B
DyLight 405 Labeled NBP2-13167V
DyLight 488 Labeled NBP2-13167G
DyLight 550 Labeled NBP2-13167R
DyLight 650 Labeled NBP2-13167C
FITC Labeled NBP2-13167F

Additional ERManI Products

Bioinformatics Tool for ERManI Antibody (NBP2-13167H)

Discover related pathways, diseases and genes to ERManI Antibody (NBP2-13167H). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for ERManI Antibody (NBP2-13167H)

Discover more about diseases related to ERManI Antibody (NBP2-13167H).
 

Pathways for ERManI Antibody (NBP2-13167H)

View related products by pathway.

Research Areas for ERManI Antibody (NBP2-13167H)

Find related products by research area.

Blogs on ERManI

There are no specific blogs for ERManI, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our ERManI Antibody (3C2) [HRP] and receive a gift card or discount.

Bioinformatics

Gene Symbol MAN1B1