ERK1 Antibody Pair

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Summary
Product Discontinued
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    • Catalog Number
      H00005595-PW1
    • Availability
      Product Discontinued

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ERK1 Antibody Pair Summary

Description
Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

  • Antibody pair for IP: mouse monoclonal anti-MAPK3 (300 ug)
  • Antibody pair for WB: mouse monoclonal anti-MAPK3 (50 ug)
  • Clonality
    Polyclonal
    Gene
    MAPK3
    Purity
    Immunogen affinity purified

    Applications/Dilutions

    Dilutions
    • Immunoprecipitation
    • Western Blot

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4
    Preservative
    No Preservative
    Purity
    Immunogen affinity purified

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for ERK1 Antibody Pair

    • EC 2.7.11
    • ERK1
    • ERK-1
    • ERK1p44-MAPK
    • ERT2
    • Extracellular signal-regulated kinase 1
    • extracellular signal-related kinase 1
    • HS44KDAP
    • HUMKER1A
    • Insulin-stimulated MAP2 kinase
    • MAP kinase 1
    • MAP kinase 3
    • MAP kinase isoform p44
    • MAPK 1
    • MAPK 3
    • MAPK3
    • MGC20180
    • Microtubule-associated protein 2 kinase
    • Mitogen-activated protein kinase 1
    • mitogen-activated protein kinase 3
    • P44ERK1
    • p44-ERK1
    • p44mapk
    • PRKM3
    • PRKM3EC 2.7.11.24

    Background

    p44 MAP Kinase (Erk1) is a member of a family of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth and differentiation (1,2). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) (3). Erk1 is also known to autophosphorylate on tyrosine (3).

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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    Product General Protocols

    Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

    Video Protocols

    WB Video Protocol

    FAQs for ERK1 Antibody Pair (H00005595-PW1) (0)

    There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

    Additional ERK1 Products

    Research Areas for ERK1 Antibody Pair (H00005595-PW1)

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    Blogs on ERK1.


      Read full blog post.


      Read full blog post.

    The role of c-Fos in the regulation of the JC virus gene transcription
    c-Fos is a member of the AP-1 transcription factor family under the Fos protein family umbrella, alongside Fra-1, Fra-2 and Fos-B.  Also in the AP-1 transcription family are the Jun proteins, c-Jun, Jun-B and Jun-D.  Each member of the AP-1 transcri...  Read full blog post.

    The effects of curcumin on IKB Alpha and the NFkB signaling pathway
    The IKK complex, or inhibitor of NFkB kinase, is composed of IKK alpha and IKK beta.  These kinases are at the core of the NFkB signaling cascade.  The NFkB family is made up of transcription factors that are kept inactive in the cytoplasm through...  Read full blog post.

    MAPK3/ERK1 - A signal transduction pathway with roles in development and disease
    Mitogen-activated protein kinases (MAPKs) are important signaling proteins needed to transmit and relay extracellular stimuli and to illicit intracellular responses (1). The MAPK family of proteins are serine/threonine kinases that are able to phos...  Read full blog post.

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    Bioinformatics

    Gene Symbol MAPK3