Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
Protein G purified
Western Blot 1 - 5 ug/ml
For WB: Use at a concentration of 1-5 ug/ml. Predicted molecular weight: 59 kDa.Chromatin Immunoprecipitation was reported in scientific literature. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
59 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NBP1-41194 in the following applications:
Alternate Names for ER beta/NR3A2 Antibody (7B10.7)
estrogen receptor 2 (ER beta)
estrogen receptor beta 4
estrogen receptor beta
Nuclear receptor subfamily 3 group A member 2
The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE's).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.