Equine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• Reactivity: Eq
• Applications: ELISA
• Conjugate: Biotin

Equine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL1B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Equine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• catabolin
• IL1 beta
• IL-1 beta
• IL-1
• IL1B
• IL-1b
• IL1-BETA
• IL-1F2
• IL1F2IL-1 beta
• interleukin 1, beta
• interleukin-1 beta
• preinterleukin 1 beta
• pro-interleukin-1-beta

Background

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Publications for IL-1 beta/IL-1F2 (DY3340)(5)

Publications using DY3340

• Andrews, KM;Berghaus, LJ;Hart, KA; Effects of mixed polyphenol supplementation on lower airway inflammation in horses with Equine Asthma Syndrome Journal of equine veterinary science 2025-08-30 [PMID: 40889730] (Equine)
• Terlinden, A;Jacquet, S;Manivong, S;Cullier, A;Cassé, F;Legendre, F;Garcia, AA;Roullin, G;Moldovan, F;Sirois, P;Banquy, X;Galéra, P;Audigié, F;Demoor, M;Bertoni, L; Double-blinded, randomized tolerance study of a biologically enhanced Nanogel with endothelin-1 and bradykinin receptor antagonist peptides via intra-articular injection for osteoarthritis treatment in horses BMC veterinary research 2024-12-04 [PMID: 39633332] (Equine)
• Morales-Vázquez, MM;Meza-Serrano, E;Lara-Pereyra, I;Acuña-González, RJ;Alonso-Morales, R;Hayen-Valles, S;Boeta, AM;Zarco, L;Lozano-Cuenca, J;López-Canales, JS;Flores-Herrera, H; Equine Placentitis in Mares Induces the Secretion of Pro-Inflammatory Cytokine eIL-1? and the Active Extracellular Matrix Metalloproteinase (MMP)-9 Veterinary sciences 2023-08-22 [PMID: 37756054] (Equine)
• MJ Anderson, AS Ibrahim, BR Cooper, AD Woolcock, GE Moore, SD Taylor Effects of administration of ascorbic acid and low-dose hydrocortisone after infusion of sublethal doses of lipopolysaccharide to horses J Vet Intern Med, 2020-10-07;0(0):. 2020-10-07 [PMID: 33026127] (Equine)
• Katie L. Edwards, Michele A. Miller, Jessica Siegal-Willott, Janine L. Brown Serum Health Biomarkers in African and Asian Elephants: Value Ranges and Clinical Values Indicative of the Immune Response Animals (Basel) 2020-09-27 [PMID: 32992555] (Elephant)

FAQs for IL-1 beta/IL-1F2 (DY3340). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: IL1B