Epac2 Antibody (SR1071) - BSA Free

Western Blot: Epac2 Antibody (SR1071) [NBP3-22082] - Western blot analysis using NBP3-22082 in Human fetal brain lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: SR1071
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Epac2 Antibody (SR1071) - BSA Free Summary

• Description: Novus Biologicals Rabbit Epac2 Antibody (SR1071) - BSA Free (NBP3-22082) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Epac2 (Uniprot #: Q8WZA2)
• Specificity: Detects endogenous levels of total Epac2
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RAPGEF4
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 116 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Epac2 Antibody (SR1071) - BSA Free

• cAMP-GEFII
• cAMP-regulated guanine nucleotide exchange factor II
• CGEF2
• CGEF2EPAC 2
• EPAC 2
• Epac2
• Exchange factor directly activated by cAMP 2
• Exchange protein directly activated by cAMP 2
• Nbla00496
• putative protein product of Nbla00496
• Rap guanine nucleotide exchange factor (GEF) 4
• rap guanine nucleotide exchange factor 4
• RAP guanine-nucleotide-exchange factor (GEF) 4
• RAPGEF4

Background

Epac2, also known as Rap Guanine Nucleotide Exchange Factor (GEF) 4, is a guanine nucleotide exchange factor for RAP1A, RAP1B and RAP2A small GTPases. Studies have shown that EPAC2 has a significant role in the development of type 2 diabetes. EPAC2 has also been studied in relation to ataxia, neuronitis, osteoporosis and pancreatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAPGEF4