EMMPRIN/CD147 Antibody (109403) [Unconjugated]

Images

 
Western blot shows lysates of human brain (cerebellum) tissue, human heart tissue, and human liver tissue. PVDF membrane was probed with 0.2 µg/mL of Mouse Anti-Human EMMPRIN/CD147 Monoclonal Antibody (Catalog # ...read more
Genetic Strategies: Western blot shows lysates of HEK293T human embryonic kidney parental cell line and EMMPRIN/CD147 knockout HEK293T cell line (KO). PVDF membrane was probed with 0.2 µg/mL of Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, KO
Clone
109403
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
     

Genetic Strategies

   

Order Details

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Catalog# & Formulation Size Price

EMMPRIN/CD147 Antibody (109403) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human EMMPRIN/CD147
Ala22-His205
Accession # Q54A51
Specificity
Detects human EMMPRIN/CD147 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant mouse EMMPRIN is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
BSG
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Knockout Validated
  • Western Blot 0.2 ug/mL
Publications
Read Publications using
MAB972 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for EMMPRIN/CD147 Antibody (109403) [Unconjugated]

  • 5F7
  • basigin (Ok blood group)
  • Basigin
  • BSG
  • CD147 antigen
  • CD147
  • Collagenase stimulatory factor
  • EMMPRIN
  • EMMPRINTCSF
  • Extracellular matrix metalloproteinase inducer
  • Leukocyte activation antigen M6
  • M6
  • OK blood group antigen
  • OK
  • Tumor cell-derived collagenase stimulatory factor

Background

EMMPRIN, also known as basigin and CD147, is a type I membrane protein belonging to the immunoglobulin superfamily. It is a multifunctional protein involved in reproduction, neural function, inflammation and tumor invasion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for EMMPRIN/CD147 Antibody (MAB972)(6)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA Development, Flow Cytometry, Western Blot.


Filter By Application
ELISA Development
(1)
Flow Cytometry
(1)
Western Blot
(4)
All Applications
Filter By Species
Human
(6)
All Species
Showing Publications 1 - 6 of 6.
Publications using MAB972 Applications Species
P Wang, X Hao, X Li, Y Yan, W Tian, L Xiao, Z Wang, J Dong Curcumin inhibits adverse psychological stress-induced proliferation and invasion of glioma cells via down-regulating the ERK/MAPK pathway Journal of Cellular and Molecular Medicine, 2021;0(0):. 2021 [PMID: 34169637] (Western Blot, Human) Western Blot Human
M Aoki, K Koga, M Miyazaki, M Hamasaki, N Koshikawa, M Oyama, H Kozuka-Hat, M Seiki, BP Toole, K Nabeshima CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts BMC Cancer, 2019;19(1):912. 2019 [PMID: 31510956] (Western Blot, Human) Western Blot Human
AP Andersen, J Samsøe-Pet, EK Oernbo, E Boedtkjer, JMA Moreira, M Kveiborg, SF Pedersen The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms Int. J. Cancer, 2018;0(0):. 2018 [PMID: 29363134] (Western Blot, Human) Western Blot Human
Määttä M, Tervahartiala T, Kaarniranta K, Tang Y, Yan L, Tuukkanen J, Sorsa T Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids. Curr. Eye Res., 2006;31(11):917-24. 2006 [PMID: 17114117] (Western Blot, Human) Western Blot Human
Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, Seiki M Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells. J. Biol. Chem., 2006;281(49):37576-85. 2006 [PMID: 17050542] (Flow Cytometry, Human) Flow Cytometry Human
Haug C, Lenz C, Diaz F, Bachem MG Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells. Arterioscler. Thromb. Vasc. Biol., 2004;24(10):1823-9. 2004 [PMID: 15319264] (ELISA Development, Human) ELISA Development Human

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Bioinformatics

Gene Symbol BSG
Uniprot