Eg5 Antibody

Images

 
Western Blot: Eg5 Antibody [NB100-57514] - Detection of Human EG5/KIF11 on HeLa whole cell lysate using NB100-57514. EG5/KIF11 was also immunoprecipitated by rabbit anti-EG5/KIF11 antibody NB100-57513.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

Eg5 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1006 and the C-terminus (residue 1056) of human kinesin-related motor protein Eg5 (kinesin family member 11) using the numbering given in entry NP_004514.2 (GeneID 3832).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KIF11
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2 - 5 ug/mg lysate
Positive Control
Eg5 Lysate (NBL1-12284)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Eg5 Antibody

  • Eg5
  • HKSP
  • kinesin family member 11
  • kinesin-like 1
  • Kinesin-like protein 1
  • kinesin-like protein KIF11
  • Kinesin-like spindle protein HKSP
  • Kinesin-related motor protein Eg5
  • KNSL1TRIP-5
  • thyroid receptor interacting protein 5
  • Thyroid receptor-interacting protein 5
  • TR-interacting protein 5
  • TRIP5EG5

Background

The kinesin superfamily of proteins consists of forty five KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. EG5/KIF11 plays a role in spindle-pole formation and chromosome positioning and separation. Alternate names for EG5/KIF11 include kinesin-like protein KIF11, kinesin-related motor protein Eg5, kinesin-like spindle protein HKSP, thyroid receptor-interacting protein 5, TRIP-5, kinesin-like protein 1, and KNSL1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KIF11
Entrez
Uniprot