EDA2R/TNFRSF27/XEDAR Antibody

Western Blot: EDA2R/TNFRSF27/XEDAR Antibody [H00060401-D01P] - Analysis of EDA2R expression in mouse liver.

Western Blot: EDA2R/TNFRSF27/XEDAR Antibody [H00060401-D01P] - Analysis of EDA2R expression in transfected 293T cell line by EDA2R polyclonal antibody.Lane 1: EDA2R transfected lysate(32.70 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

EDA2R/TNFRSF27/XEDAR Antibody Summary

• Immunogen: EDA2R (NP_068555.1, 1 a.a. - 297 a.a.) full-length human protein. MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAFQLSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEADKTAKEESLFPVPPSKETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCTSESHSHWVHSPIECTELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVPFEVPSP
• Specificity: EDA2R - ectodysplasin A2 receptor,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EDA2R
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for EDA2R/TNFRSF27/XEDAR Antibody

• ectodysplasin A2 receptor
• EDA2R
• EDA-A2 receptor
• EDAA2R
• EDA-A2R
• EDAA2Rtumor necrosis factor receptor superfamily member XEDAR
• EDAR2
• TNFRSF27
• XEDAR
• XEDARTNFRSF27tumor necrosis factor receptor superfamily member 27
• X-linked ectodysplasin-A2 receptor

Background

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for EDA2R/TNFRSF27/XEDAR Antibody (H00060401-D01P)(1)

Publication using H00060401-D01P

• Staropoli JF, Li H, Chun SJ et al. Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7. Genomics. 2015-01-31 [PMID: 25645699]

Bioinformatics

• Gene Symbol: EDA2R
• Entrez:
  • 60401(Human)
• Uniprot:
  • NP_068555.1(Human)