ECE-2 Antibody (233914) [Janelia Fluor® 549]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 233914
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Janelia Fluor 549

ECE-2 Antibody (233914) [Janelia Fluor® 549] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ECE-2
  Val104-Leu787
  Accession # O60344
• Specificity: Detects human ECE-2 in direct ELISAs and Western blots. In Western blots, 30% cross-reactivity with recombinant human (rh) ECE‑1 and no cross-reactivity with rhKELL is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: ECE2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ECE-2 Antibody (233914) [Janelia Fluor® 549]

• EC 3.4.24
• EC 3.4.24.71
• ECE2
• ECE-2
• endothelin converting enzyme 2
• endothelin-converting enzyme 2
• KIAA0604MGC2408
• MGC17664
• MGC78487

Background

Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 (PubMed 11718899)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ECE2