E-Selectin/CD62E Antibody (BBIG-E1) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: Flow, IP, B/N, CyTOF-ready, ICC/IF
• Clone: BBIG-E1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

E-Selectin/CD62E Antibody (BBIG-E1) [Alexa Fluor® 488] Summary

• Immunogen: Activated HUVEC human umbilical vein endothelial cells
• Specificity: This antibody binds to CHO cells transfected with human E-Selectin. It does not bind to COS cells transfected with human PECAM‑1, P‑Selectin, L‑Selectin, VCAM‑1, or ICAM‑1.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Adhesion Blockade
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for E-Selectin/CD62E Antibody (BBIG-E1) [Alexa Fluor® 488]

• CD62 antigen-like family member E
• CD62E antigen
• CD62E
• ELAM
• ELAM1
• ELAM-1
• ELAM1E-selectin
• endothelial adhesion molecule 1
• Endothelial leukocyte adhesion molecule 1
• ESEL
• E-Selectin
• LECAM2
• leukocyte endothelial cell adhesion molecule 2
• Leukocyte-endothelial cell adhesion molecule 2
• SELE
• selectin E

Background

E-Selectin, also known as ELAM-1, is a transmembrane glycoprotein that is transiently expressed on activated vascular endothelial cells. E-Selectin binds to sialyated, fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.