DSCAM Antibody

Images

 
Western Blot: Dscam Antibody [NB100-41390] - (1ug/ml) staining of NIH/3T3 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

DSCAM Antibody Summary

Immunogen
Peptide with sequence C-DSWDSAQRTKDVSPQ corresponding to internal region according to NP_996770.1.
Specificity
This antibody is expected to recognise both reported isoforms (NP_001380.2 and NP_996770.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
DSCAM
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 - 6 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 170 kDa band observed in human brain (cerebellum) lysates (calculated MW of 174 kDa band according to NP_996770.1).
Publications
Read Publication using NB100-41390.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DSCAM Antibody

  • CHD2-42
  • CHD2-52
  • Down syndrome cell adhesion molecule
  • DSCAM
  • human CHD2-52 down syndrome cell adhesion molecule, 10CHD2

Background

The Dscam gene encodes a large family of axon guidance receptors and immune receptors via alternative splicing, generating over 38000 isoforms. The gene has been shown to be required for axon guidance, specifically targeting individual neurons to their targets. The gene has also been shown to be involved in the immune system of the fly; different isoforms interact with different pathogens to elicit an immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DSCAM Antibody (NB100-41390)(1)


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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DSCAM
Entrez
Uniprot