Human Doublecortin ELISA Kit (Colorimetric)

ELISA: Human Doublecortin ELISA Kit (Colorimetric) [NBP2-82453] - Samples were spiked with high concentrations of Human Doublecortin and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human Doublecortin ELISA Kit (Colorimetric) [NBP2-82453] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, cell supernatant, and other biological fluids
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.09 ng/mL

Human Doublecortin ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human Doublecortin in samples. No Significant cross-reactivity or interference between Human Doublecortin and analogues was observed.
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.09 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 4.47
• Intra-Assay: CV% < 4.44
• Spike Recovery: 84-104%
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: DCX

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Doublecortin ELISA Kit (Colorimetric)

• DBCN
• Doublecortex
• Doublecortin
• Doublin
• FLJ51296
• Lissencephalin-X
• LISX
• Lis-X
• X-linked (doublecortin)

Background

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: DCX