Doublecortin Products

Antibodies
ELISA Kits
Human Doublecortin ELISA Kit ...
Human Doublecortin ELISA Kit (Colo...
NBP2-82453
Species: Hu
Applications: ELISA
Lysates
Doublecortin Overexpression L ...
Doublecortin Overexpression Lysate
NBP2-11166
Species: Hu
Applications: WB
Doublecortin Overexpression L ...
Doublecortin Overexpression Lysate
NBL1-09761
Species: Hu
Applications: WB
Doublecortin Overexpression L ...
Doublecortin Overexpression Lysate
NBL1-09760
Species: Hu
Applications: WB
Proteins
Recombinant Human Doublecorti ...
Recombinant Human Doublecortin GST...
H00001641-P01
Species: Hu
Applications: WB, DB, ELISA, MA, AP
Doublecortin Recombinant Prot ...
Doublecortin Recombinant Protein A...
NBP2-55074PEP
Species: Hu
Applications: AC

Description

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Alternate Names
  • doublecortin
  • Doublin
  • FLJ51296
  • Lissencephalin-X
  • Lis-X
  • X-linked (doublecortin)

Research Areas for Doublecortin

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Phospho-Specific
Signal Transduction