DOT1L Antibody (8B2)

Western Blot: DOT1L Antibody (8B2) [H00084444-M02] - detection against Immunogen (37.4 KDa) .

Product Discontinued

DOT1L Antibody (8B2) Summary

• Immunogen: DOT1L (NP_115871, 3 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLR
• Specificity: DOT1L - DOT1-like, histone H3 methyltransferase (S. cerevisiae) (8B2)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: DOT1L
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DOT1L Antibody (8B2)

• DOT1L
• DOT1-like protein
• DOT1-like, histone H3 methyltransferase (S. cerevisiae)
• EC 2.1.1.43
• H3-K79-HMTase
• KIAA1814DKFZp586P1823
• KMT4
• KMT4H3 lysine-79 specific
• Lysine N-methyltransferase 4

Background

DOT1 is an evolutionarily conserved histone methyltransferase that methylates lysine-79 of histone H3 in the core domain. Unlike other histone methyltransferases, DOT1 does not contain a SET domain, and it specifically methylates nucleosomal histone H3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DOT1L
• Entrez:
  • 84444(Human)
• Uniprot:
  • NP_115871(Human)