DOCK4 Antibody - BSA Free

Immunohistochemistry: DOCK4 Antibody - BSA Free [NBP3-47972] - Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using ( DOCK4 Antibody) at dilution of 1:200

Immunoprecipitation: DOCK4 Antibody - BSA Free [NBP3-47972] - IP Result of anti-DOCK4 (IP:, 5ug; Detection: 1:500) with HeLa cells lysate 1800ug.

• Reactivity: Hu
• Applications: ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

DOCK4 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit DOCK4 Antibody - BSA Free (NBP3-47972) is a polyclonal antibody validated for use in IHC, ELISA and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: dedicator of cytokinesis 4. (Uniprot# Q8N1I0)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DOCK4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Immunoprecipitation 1:200-1:1000
• Theoretical MW: 225 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for DOCK4 Antibody - BSA Free

• dedicator of cytokinesis 4
• dedicator of cytokinesis protein 4
• KIAA0716FLJ34238
• MGC134911
• MGC134912

Background

DOCK4 is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DOCK4