DOC1 Antibody

Western Blot: DOC1 Antibody [NBP2-16208] - Sample (30 ug of whole cell lysate) A: HCT116 B: MCF-7 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Discontinued

DOC1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human DOC1. The exact sequence is proprietary.
• Localization: Cytoplasm; Membrane; Nucleus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FILIP1L
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 130 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for DOC1 Antibody

• 90 kDa GPBP-interacting protein
• downregulated in ovarian cancer 1 81 kDa isoform
• filamin A interacting protein 1-like
• GIP130a
• GIP130b
• GIP130c

Background

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: FILIP1L
• Uniprot:
  • Q4L180(Human)