Dnmt3L Antibody Pair

Product Discontinued

Dnmt3L Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00029947-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human DNMT3L.
  
  
• Capture antibody: rabbit MaxPab affinity purified polyclonal anti-DNMT3L (100 ug)
• Detection antibody: mouse purified polyclonal anti-DNMT3L (20 ug)
• Standard Curve Range: 3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: DNMT3L

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Dnmt3L Antibody Pair

• DNA (cytosine-5-)-methyltransferase 3-like
• DNA (cytosine-5)-methyltransferase 3-like
• human cytosine-5-methyltransferase 3-like protein, 10cytosine-5-methyltransferase 3-like protein
• MGC1090

Background

DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: DNMT3L